From Obesity to Diabetes
Author: Juergen Eckel, Karine Clément
Affiliation: Juergen Eckel, German Diabetes Center, Düsseldorf, Germany; Karine Clément, Sorbonne Université/INSERM, Paris, France
Publisher: Springer Nature
Publication Date: 2022
ISBN 10: 3030999947
ISBN 13: 9783030999940
eISBN: 9783030999957
Edition: 1st
Affiliation: Juergen Eckel, German Diabetes Center, Düsseldorf, Germany; Karine Clément, Sorbonne Université/INSERM, Paris, France
Publisher: Springer Nature
Publication Date: 2022
ISBN 10: 3030999947
ISBN 13: 9783030999940
eISBN: 9783030999957
Edition: 1st
Description:
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
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