Treatment and Prevention of Malaria

Image of the book cover for 'Treatment and Prevention of Malaria'
Author: Henry Staines, Sanjeev Krishna
Affiliation: St. George's University of London, UK
Publisher: Springer Nature
Publication Date: 2012
ISBN 10: 3034604793
ISBN 13: 9783034604796
eISBN: 9783034604802
Edition: 1st
Description:
Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
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